There is a link between cannabis use and lower dementia risk

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Summary: Recreational cannabis use may be associated with a significant decrease in the odds of experiencing subjective cognitive decline (SCD) in adults over 45.
Key Facts: Recreational cannabis use was associated with a significantly lower risk of subjective cognitive decline in adults over 45.
Source: Bentham Science Publishers A new study by Upstate Medical University researchers shows that recreational cannabis use may offer protection against cognitive decline.
“We do not know if non-medical cannabis leads to better cognition or the other way around if those with better cognition are more likely to use non-medical cannabis.
“We need longitudinal studies to see long term if non-medical cannabis use is protecting our cognition over time.
“Based on our findings, we don’t see the CBD in medical cannabis being beneficial for cognitive health,” Wong said.
“Association Between Cannabis Use and Subjective Cognitive Decline: Findings from the Behavioral Risk Factor Surveillance System (BRFSS)” by Zhi Chen et al.
Objective: The objective of this study was to examine whether cannabis consumption reason, frequency, and method are associated with subjective cognitive decline (SCD).

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In summary, among adults over 45, recreational cannabis use may be significantly associated with a lower likelihood of subjective cognitive decline (SCD). Researchers discovered that recreational users had a 96% lower likelihood of reporting SCD than non-users after analyzing data from the CDC’s 2021 Behavioral Risk Factor Surveillance System.

The study’s authors stress the need for longitudinal research to fully understand the long-term effects, but this intriguing finding points to possible protective effects of cannabis on cognition. The study highlights the significance of distinguishing between medical and recreational use in research, and despite its limitations, it adds to the growing discourse surrounding cannabis use and cognitive health.

Important Information:.

Adults over 45 who use cannabis recreationally have a significantly lower risk of experiencing subjective cognitive decline.

The study is distinctive in that it looks at the kind, frequency, and mode of cannabis use while concentrating on an older demographic.

The odds of SCD were not significantly affected by the frequency or method of cannabis consumption, which suggests that the THC content may play a protective role against cognitive decline.

Bentham Science Publishers is the source.

Researchers from Upstate Medical University have found that smoking cannabis recreationally may help prevent cognitive decline.

Professor Roger Wong, Ph.D. and Master of Public Health (MPH) candidate Zhi Chen conducted the study. D. , MPH, MSW, examined a sizable CDC data set and discovered that non-medical cannabis use—such as recreational use—was linked to 96 percent lower odds of subjective cognitive decline (SCD) when compared to non-users.

Not significantly, but medical and dual use (medical and non-medical) were also linked to lower odds of SCD. The frequency and method of cannabis consumption did not show any significant correlation with SCD.

SCD is a significant outcome of interest because previous studies have shown that people with SCD are twice as likely to develop dementia, for which there is presently no known cure or effective preventive measures.

Although Wong is quick to point out the study had several limitations and that these results are just a snapshot of one year, he said the results were surprising because prior research had found negative associations between cannabis use and cognitive decline.

“We think that cannabis may protect against cognitive decline, but more research is needed as this is only a snapshot of 2021,” stated Wong, an assistant professor in the Department of Public Health and Preventive Medicine.

“We don’t know if using non-medical cannabis improves cognition or if using non-medical cannabis makes people with better cognition more likely to use it.”.

To determine whether long-term use of cannabis for non-medical purposes protects our cognitive abilities over time, longitudinal studies are necessary. That is something we do not yet know, but because cannabis is still illegal on a federal level, research on it is hampered. “.

For this investigation, data from 4,744 U.S. S. adults in the 2021 Behavioral Risk Factor Surveillance System (BRFSS) who are 45 years of age or older. SCD was defined as a self-reported rise in memory loss or confusion during the previous year.

After applying sample weights, imputing missing data, and adjusting for sociodemographic, health, and substance use factors, the odds of SCD by cannabis use reason, frequency, and method were investigated.

This research is distinct from others because it focuses on middle-aged and older adults and examines three aspects of cannabis use: the type of use (medical or non-medical), the frequency of use, and the mode of use (smoking, vaping, eating, or dabbing).

“We looked at all the different dimensions of cannabis use, which is why I think this study is so great,” the researcher stated. I don’t think a study like this has ever been done before, so the inclusion of all three is a major contribution to the research. “.

When other studies with younger participants found a negative correlation between cannabis use and brain health, Wong said he was surprised that mode and frequency had no effect on SCD, suggesting that participant age may have played a role in the inconsistent findings.

Chen’s final project for the Advanced Biostatistics course in Wong’s MPH program was the study, which was published in Current Alzheimer Research.

“I used the information and analytical abilities I acquired in the Public Health Methods concentration courses to this study,” Chen stated.

“Prof. Wong helped me every step of the way, from coming up with a research question to writing the entire manuscript. We are privileged to have outstanding instructors in our program who prepare us to become comprehensive public health practitioners capable of working in epidemiology and biostatistics. “.

The study’s limitations were acknowledged by the authors, one of which being that state-specific cannabis regulations could not have been taken into account. As a result, selection bias may have occurred if distinct states’ populations were over- or underrepresented in relation to cannabis use, depending on the measure used.

One of the study’s strengths is the use of a national data set, which improves the findings’ generalizability. According to Wong, the compounds that make up cannabis determine the degree of protection experienced during medical and non-medical use. While non-medical cannabis has higher THC concentrations, medical cannabis has higher CBD concentrations.

Stress relief and better sleep are two common reasons non-medical cannabis users use it. Cannabis may offer protection against SCD through improving sleep and reducing chronic stress, both of which are factors that raise the risk of dementia. The main purpose of medical marijuana is to treat pain.

“Our research indicates that there is no benefit to cognitive health from the CBD in medicinal cannabis,” Wong stated.

on this news article about cannabis and dementia research.

Noman Akbar wrote this.

Bentham Science Publishers, the source.

Bentham Science Publishers, Noman Akbar, can be reached.

Image: Neuroscience News is credited with this image.

Exclusive access to original research.

Zhi Chen and colleagues’ article “Association Between Cannabis Use and Subjective Cognitive Decline: Findings from the Behavioral Risk Factor Surveillance System (BRFSS)”. Present Research on Alzheimer’s Disease.

Abstraction.

Connection between Cannabis Consumption and Subjective Cognitive Decline: Results from the Behavioral Risk Factor Surveillance System (BRFSS).

Background: As more states have legalized both medical and non-medical cannabis use, the country’s cannabis consumption has grown dramatically. Nonetheless, little research has been done to determine whether cannabis use, especially in terms of its various forms, may be linked to cognitive function.

This study set out to investigate whether the purpose, frequency, and mode of cannabis consumption are related to subjective cognitive decline (SCD).

Methods: 4,744 U.S. customers provided data. s. individuals in the 2021 Behavioral Risk Factor Surveillance System (BRFSS) who are 45 years of age or older. Self-reported increases in confusion or memory loss over the previous year were associated with SCD. Odds of SCD according to the purpose, frequency, and techniques (e.g. G. After applying sample weights, adjusting for sociodemographic, health, and substance use covariates, and imputed missing data, the effects of, smoke, eat, and vaporize) were investigated using multiple logistic regression.

Findings: Non-medical cannabis use was substantially linked to 96% lower odds of sickle cell disease (SCD) compared to non-users (aOR=0.04, 95% CI=0.01-0.44, p<. 1. Medical (aOR=0.46, 95% CI=0.06-3.61, p =. 46) and concurrent use for both medical and non-medical purposes (aOR=0.30, 95% CI=0.03-2.92, p =. 30) were also, albeit not statistically significantly, linked to lower odds of SCD. The frequency and mode of cannabis consumption did not significantly correlate with SCD.

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